“Preserved” glucagon secretion in fulminant type 1 diabetes
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چکیده
منابع مشابه
Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes?
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OBJECTIVE To evaluate if insulin has a suppressive effect on the glucagon secretion stimulated by arginine in type 1 diabetes. RESEARCH DESIGN AND METHODS The alpha-cell response to an i.v. bolus of arginine (150mgkg(-1)) followed by an infusion of arginine (10mgkg(-1)min(-1)) was studied in random order during either low dose infusion (LDT) or high dose infusion (HDT) of insulin in ten patie...
متن کاملImmunological Aspects of Fulminant Type 1 Diabetes in Chinese
Background. Fulminant type 1 diabetes (FT1D) is a novel subtype of type 1 diabetes characterized by extremely rapid onset and complete deficiency of insulin due to the destruction of pancreatic β cells. However, the precise mechanisms underlying the etiology of this disease remain unclear. Methods. A total of 22 patients with FT1D and 10 healthy subjects were recruited. Serum antibodies to GAD,...
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Type 1 diabetes mellitus (T1DM), one of two major forms of diabetes, results from nearly complete destruction of pancreatic beta (┚) cells. According to the classification of diabetes made by the American Diabetes Association, T1DM is divided into two subtypes: immunemediated (type 1A) and idiopathic (type 1B) (American Diabetes Association, 2008). Fulminant type 1 diabetes mellitus (FT1DM), wh...
متن کاملFulminant type 1 diabetes: a nationwide survey in Japan.
OBJECTIVE To describe the clinical and immunologic characteristics of fulminant type 1 diabetes, a novel subtype of type 1 diabetes, we conducted a nationwide survey. RESEARCH DESIGN AND METHODS History and laboratory data, including islet-related autoantibodies, were examined in 222 patients with fulminant and nonfulminant type 1 diabetes in our hospitals in addition to another 118 patients ...
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ژورنال
عنوان ژورنال: Journal of Diabetes Investigation
سال: 2018
ISSN: 2040-1116
DOI: 10.1111/jdi.12946